This book is a compilation of the various recently developed techniques emphasizing better chemical processes and products, with state-of-the-art contributions by world-renowned leaders in process design and optimization. It covers various areas such as grass-roots design, retrofitting, continuous and batch processing, energy efficiency, separations, and pollution prevention, striking a balance between fundamental techniques and applications. The book also contains industrial applications and will serve as a good compilation of recent industrial experience for which the process design and optimization techniques were applied to enhance sustainability. Academic researchers and industrial practitioners will find this book useful as a review of systematic approaches and best practices in sustainable design and optimization of industrial processes. The book is accompanied by some electronic supplements (i.e., models and programs) for selected chapters. Readership: Advanced undergraduates and graduate students in chemical process design and optimization; non-experts interested in clean process design.